Search results for "Tyrode solution"

showing 4 items of 4 documents

Inhibition by parasympathetic nerve stimulation of the release of the adrenergic transmitter

1970

Isolated rabbit atria were perfused with Tyrode solution containing (+)-amphetamine. Electrical stimulation of the right postganglionic sympathetic fibres caused an output of noradrenaline which was significantly decreased by simultaneous stimulation of the vagus nerves.

Atropinemedicine.medical_specialtyDextroamphetamineSympathetic Nervous SystemStellate GanglionPharmacology toxicologyAdrenergicStimulationSimultaneous stimulationNorepinephrineInternal medicinemedicineAnimalsHeart AtriaAmphetaminePharmacologyChemistryHeartVagus NerveGeneral MedicineParasympathetic nerveElectric StimulationPerfusionEndocrinologyTyrode solutionAutonomic Fibers PostganglionicRabbitsmedicine.drugNaunyn-Schmiedebergs Archiv f�r Pharmakologie
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�ber das Verhalten und Reaktionsverm�gen von glatter Muskulatur und Herzmuskulatur in chloridfreiem Medium (Methylsulfat-Tyrode-L�sung)

1961

Um die Bedeutung der Chlorid-Ionen fur die Funktion von glatter Muskulatur und Herzgewebe zu untersuchen, wurden die Chlorid-Ionen der Tyrodelosung durch die einwertigen, nicht permeierenden und indifferenten Methylsulfat-Ionen ersetzt. Die Versuche wurden am Meerschweinchen-Ileum, Kaninchen-Duodenum, Ratten-Uterus, spontan schlagenden Vorhof des Meerschweinchens und am Froschherz nach Straub durchgefuhrt. Keines der genannten Organe reagierte beim Uberfuhren in chloridfreies Medium oder bei stundenlangem Aufenthalt in Methylsulfat-Tyrodelosung mit einer wesentlichen Funktionsanderung. Wahrend die Herzmuskulatur in chloridfreiem Milieu unverandert auf positiv oder negativ inotrop wirksame S…

PharmacologyChemistryPharmacology toxicologyTyrode solutionmedicineGeneral MedicineMethyl SulfateMedicinal chemistryChlorideFree mediummedicine.drugNaunyn-Schmiedeberg's Archiv f�r Experimentelle Pathologie und Pharmakologie
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Über die Wirkung von Prostaglandin E1 auf den Ca-Haushalt isolierter Meerschweinchenherzen

1967

The stimulatory effect of PGE1 on different functions of isolated guinea-pig hearts (Langendorff method, Tyrode solution) was coupled with an increase in the rate of45Ca uptake from the perfusion medium. The total myocardial Ca content and the amount of exchangeable cellular Ca were not affected. This action of PGE1 on the myocardial Ca metabolism seems to be related to the positive inotropic action of PGE1 and can most probably be explained by an increase in the membrane permeability to Ca ions (similar to the action of epinephrine).

PharmacologyInotropemedicine.medical_specialtyMembrane permeabilityChemistryCa metabolismCell Biologyrespiratory systemCellular and Molecular NeuroscienceEndocrinologyEpinephrineInternal medicinemedicineTyrode solutionMolecular Medicinelipids (amino acids peptides and proteins)Molecular BiologyPerfusioncirculatory and respiratory physiologymedicine.drugExperientia
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Die Hemmung der Aufnahme vonα-Methylnoradrenalin in das Herz durch sympathomimetische Amine

1965

Hearts of rabbits were isolated and perfused with Tyrode solution containing 10 ng/ml (−)-α-methyl noradrenaline. The uptake by the heart ofα-methyl-noradrenaline was calculated by estimating the amount of amine removed from the perfusion fluid while passing through the heart. In control experiments the mean removal ofα-methyl noradrenaline was 43,7 ± 1,6% of the amount infused. The rate of removal remained constant throughout the time period of the experiment, i.e. 20 min.

PharmacologyPerfusion fluidChromatographyStereochemistryChemistryPharmacology toxicologyTyrode solutionAmine gas treatingGeneral MedicineNaunyn-Schmiedebergs Archiv für Experimentelle Pathologie und Pharmakologie
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